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Hair loss medication Finasteride. How to get Finasteride?

Finasteride for hair. Does Finasteride really work?

Finasteride is a medicine for stopping hair loss in men and treating prostate adenoma. Slows down the conversion of testosterone to dihydrotestosterone by binding to the second type of 5-alpha reductase enzyme. Finasteride affects the root cause of baldness, but does not stimulate the growth of new hair, so it is used in conjunction with minoxidil. Holds existing hair and slows further baldness. The drug is available in pill form and is taken orally every day.

When will the first results appear?

The first results can be observed in 6-12 months. In extremely rare cases, improvements may appear within three months.

Can Finasteride build up new hair?

The drug affects the root cause and stops baldness. In some cases, using only finasteride may be accompanied by new hair growth. It is rarely possible to restore most of the lost hair, as in this case. A man took 1 mg of finasteride every day for three years and achieved good results. Usually, you can only achieve a suspension of hair loss, to stimulate growth, you will need to use Minoxidil.

How long to take finasteride?

As long as you take finasteride, it works. If you stop taking, the effect stops. Finasteride needs to be taken while your hair is dear to you, that is, all your life. Or until a new, more effective means is invented.

Finasteride dosage. Finasteride 1mg for hair regrowth

How to take Finasteride?

According to the instructions, take one pill of Propecia every day, regardless of the meal. Some participants of the forums about hair loss consider that it is better to take a pill on an empty stomach.

Can medications containing 5 mg of finasteride be used instead of 1 mg?

Yes. Many men do so to save money. But since other drugs (Proscar, Finasteride, Finast, and others) contain 5 mg of finasteride in one tablet, you need to divide each pill into 5 parts and take them every day. You will receive the same 1 mg of Finasteride daily as you would when taking Propecia. The use of alternative drugs is cheaper compared to the original with the same effectiveness.

What dosage to take?

Propecia's FDA studies have shown that a dosage of 0.05 to 5 mg provides a similar result. The difference is 5-7% better binding of 5-alpha reductase of the second type in favor of a higher dosage. This can play a big role in the high sensitivity of hair follicles to dihydrotestosterone.

Why do many men take 1 mg of Finasteride per day?

Because they have not heard about the research or they are uncomfortable to divide the 5 mg pill into 100 parts to get 0.05 mg. Or into 25 parts to get 0.2 mg.

What are the drugs based on finasteride? Finasteride generic name

Propecia - is a finasteride-based drug to stop balding. In this preparation for each tablet accounts for 1 mg of finasteride. For the treatment is taken one tablet per day.

Finpeсia - Indian analog of Propecia, which is manufactured by CIPLA. Finpecia does not differ from Propecia by composition or dosage. Each tablet contains 1 mg of finasteride. The price is much lower than the original.

Finasteride for hair loss. How long does Finasteride work?

The time of action of finasteride. How old is finasteride can keep hair?

Patient question:

Finasteride can slow the process of baldness in men with androgenetic alopecia, but not stop it at all. That is, baldness will continue, but not so fast. I understand that there are no studies that could shed light on this question. But still a lot of young guys with early signs of baldness would like to know how much they can "hold" their hair and prevent hair loss in practice.

Since Finasteride was available relatively recently, I understand that it will be difficult to answer. The same applies to side effects in the long term. But still, maybe you have some information about how much finasteride can help hold the hair?

Specialist Answer (Dr. Raysman):

You would have asked how many years you still live in the world. Each case is individual. Someone will die young, and someone old. Hair is the same.

I am a trichologist, not a predictor of the future. Male-pattern baldness is a genetic defect that is prescribed, and there are an infinite number of drugs that can affect every single person. I do not have statistics on this, but I saw with my own eyes several patients who were able to keep their hair in the same condition as they first started taking finasteride, when this medicine only appeared many years ago.

Where to buy Finasteride? Finasteride pharmacy

You can not buy Finasteride in the city pharmacy without a prescription, but on the website of our partner this drug is always available for order. Banner below:

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Finasteride for men. Hair loss drug Finasteride

What is the drug "Finasteride"?

Finasteride is the only drug for internal use and has been approved by the US FDA as a means to treat and combat androgenic alopecia in men.

At the very beginning, this drug was produced under the name “Proscar”, it was developed and intended to combat such diseases that are directly related to the prostate gland. However, those patients who suffered in parallel with androgenic alopecia, began to notice a unique “side effect” as they used “Proscar” - the hair stopped falling out, and after a certain time new hair growth was observed.

This fact gave impetus to the conduct of complex clinical research by specialists of the company. According to the research, it was decided to recycle the drug, which has a new name, which included the active component finasteride (dosage - 1 mg). Already in 1997, “Finasteride” (having a different name - “Propecia”) has been produced for the treatment of androgenic alopecia.

Does Finasteride work for hair loss? Can Finasteride regrow hair?

The effect of the drug.

The scope of use of the drug are: the top of the head, the middle region of the head, the front line of the hair, the most prone to androgenic alopecia areas of the scalp. It is noted that the first results are observed already 4 months after regular use of the product.

The action of “Finasteride” is due to the maximum effect of the active component on the hair follicles, due to the blocking of the work of 5α-reductase type 2. At the very beginning of treatment, newly growing hair can be thin, colorless and lifeless. Later they thicken, gradually acquiring a healthy appearance.

After 2 years of regular use of Propecia, you can see the maximum effect. It is believed that the patient can continue the treatment with “Finasteride” if the effect of the application is observed. If after 1 year after intensive use of the drug, the effect is not observed, it means that the drug is not subject to further use.

Since the drug acts only on the activity of 5α-reductase, after the cessation of treatment with “Finasteride”, hair loss may occur with subsequent progression of baldness. Therefore, “Finasteride” is indicated for permanent use by those patients who do not have any contraindications and sensitivity to the active ingredient.

Finasteride price. How much does Finasteride cost?

How much does Finasteride cost?

The price of finasteride is about $40 per pack of 30 tablets of 5 mg. This means preparations containing finasteride as an active substance. For example, Propecia is quite common in pharmacies and can be bought without a prescription online.

Given that you need to use 1 mg of finasteride per day, it is easy to count on how many days 30 tablets will suffice. 30 x 5 = 150 days. But if you divide the pill not into 5, but into 10 parts (in this case, the efficiency drops slightly), then finasteride will last for almost 1 year.

You can search for cheaper options. But this makes no sense, since the price of Propecia is not very high, and the effect will be better.

Thus, of all existing anti-baldness drugs, finasteride remains one of the most affordable in all respects: both in price and in availability (you can buy it at our partner’s online pharmacy).

Finasteride uses. What is Finasteride prescribed for?

Finasteride helps eliminate negative manifestations in benign prostatic hyperplasia (BPH). The drug is characterized by a narrow scope and severe restrictions on use. However, it is distinguished from a number of analogues by a high level of efficiency, due to the development of a regulated process of neoplasm cell death. Women are prescribed the drug in exceptional cases.

Under the influence of finasteride, a decrease in prostate volume is observed, which is caused by a decrease in the level of dihydrotestosterone.

Indications for use of Finasteride.

The main direction of the purpose - the treatment of benign prostatic hyperplasia of varying severity. In this case, the goal of therapy is to reduce the size of the prostate, eliminating the symptoms of the disease. Given that acute urinary retention is a sign of BPH, the drug is prescribed to prevent the onset of this symptom. In this case, the need for catheterization or transurethral resection of the prostate can be avoided.

The duration of treatment is determined individually, which affects the state of the prostate, the stage of development of the pathology, the presence of other diseases.

Using Finasteride with an enlarged prostate

The recommended dose is 5 mg (or 1 tablet) per day.

Using Finasteride (Propecia) for baldness

For the treatment of baldness in men, not pure finasteride is used, but special tablets based on it, such as Propecia. They contain additional excipients. In this case, 1 mg of the drug is prescribed per day. Fully restore the hair on the head with androgenetic alopecia will not work, because after cessation of therapy, the positive result, which was achieved, disappears. Hair begins to grow actively only during treatment with Finasteride (Propecia).

The minimum course duration is 6 months. It is recommended to extend the treatment to 2 years. If you take the drug on an ongoing basis, the desired result will be saved for a long time. After the cancellation will begin the process of hair loss. For alopecia, Finasteride is often used with Minoxidil.

How long to take Propecia with baldness?

In most cases, the duration of treatment is several months. At the initial stage, the doctor may recommend admission for 6-7 months. If necessary, the course is extended until a stable result appears.

Finasteride medication composition and packaging

The drug finasteride, intended exclusively for oral (through the mouth) consumption, is available in a single dosage form - in the form of biconvex round tablets, covered with a bright blue shell and labeled "F5" on one side.

The active ingredient of the drug is finasteride (5 mg per tablet).

The dispersed film coating of opadrai in which the tablets are coated consists of a whole complex of auxiliary components: monocrystalline cellulose, lactose monohydrate, corn starch, magnesium stearate and lauryl macrogolglycerides.

Manufacturers pack tablets into contoured vacuum blisters, accommodating seven, ten and fourteen pieces. Blisters (one to four), along with instructions for the use of the drug, are placed inside cardboard packs.

Finasteride indication

Finasteride is used to treat patients with benign prostatic hyperplasia (adenoma). Under the influence of the drug:

  • there is a significant reduction in the size of the affected gland;
  • the rate of urine outflow is maximized;
  • the probability of the development of the mechanism of acute urinary retention is significantly reduced, for the elimination of which there is a need for the use of catheterization or in performing prostatectomy operations (removal of the entire prostate gland or part thereof) and transurethral resection (minimally invasive surgical intervention aimed at rapid elimination of urinary problems) of the prostate.

Finasteride contraindications

The drug finasteride is absolutely contraindicated:

  • Patients who are hypersensitive to the main active ingredient and to individual components of the chemical composition.
  • Women of childbearing age.
  • Pregnant women.
  • For the children.

With great care, you can apply the drug to treat patients suffering from:

  • obstructive uropathy (a condition that occurs on any part of the genito-urinary tract and is accompanied by blockage of the urine flow, fraught with serious damage to the kidneys);
  • varying degrees of liver failure;
  • prostate cancer.

Finasteride mechanism of action

Finasteride slows the action of 5-alpha-reductase of the second type, which promotes the conversion of testosterone into 5-alpha-dihydrotestosterone, a substance with significantly greater activity. As a result of this process, the concentration of the newly synthesized hormone in the blood plasma and in the cells of the prostate gland is significantly reduced. This effect persists throughout the day after taking the drug.

Finasteride blocks the stimulating effect of testosterone on the growth of tumor structures. As a result of regular inhibition of the formation of 5-alpha-dihydrotestosterone, the volume of the pathologically enlarged prostate gland is significantly reduced, the maximum rate of urinary outflow is increased, and the painful symptomatology of insufficient conductivity of the urinary ducts is rapidly declining.

In patients who regularly take the drug in full accordance with the recommendations of their treating specialist, the first significant results of treatment are recorded at regular intervals:

  • the volume of the affected prostate gland begins to decrease in twelve weeks after the start of treatment;
  • significant acceleration of urine outflow occurs after 16 weeks of therapy;
  • a decrease in the overall pathological symptoms and the consequences of obstruction of the urinary tract is observed after seven months of daily treatment.

If - contrary to the prescriptions of the doctor - the patient stops taking finasteride, the disappeared-there were pathological changes in the prostate gland (together with a set of accompanying symptoms) will return within six months.

Complete absorption of finasteride by the organs of the gastrointestinal tract occurs after six to eight hours. Possessing good absorption and high penetrating ability, the drug quickly spreads through the body, easily penetrating into tissues and all kinds of biological fluids (in the ejaculate concentration rapidly reaches 5 g).

The level of bioavailability (the ability of the drug to be absorbed with maximum benefit to the body) finasteride is almost 80%. The maximum time (its value is 8-10 ng / ml) of the drug concentration in the blood plasma is two hours, and its connection with blood plasma proteins is at the level of 92%.

After overcoming the hemato-encephalic barrier, a small amount of finasteride is present in the cerebrospinal fluid within a week after the start of the therapeutic course.

With prolonged medication, an insignificant cumulation of the active substance in the tissues of the body is observed. The half-life of the drug in men, belonging to the age category from 18 to 60 years, is not less than six hours. In patients older (after seventy) age category, it is extended by two hours.

The large (almost 58%) part of the drug in the altered (in the form of metabolites) form leaves the body of the patient along with the calves, 39% - along with the urine. In patients with chronic kidney failure, some metabolites (those that are usually excreted in urine in healthy patients) can be excreted along with feces.

Where can I buy Finasteride (Propecia)? Finasteride Canada

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When to take Finasteride? Instructions

Finasteride belongs to the category of drugs that should be taken for a very long time. Therapeutic regimens are developed individually for each individual patient.

1. The drug, intended for oral use, usually takes one tablet once a day (you can both before and after food: it is only necessary that the digestive process is already started when the drug enters the gastrointestinal tract). Do not chew the tablets.

2. Finasteride can be used both for monotherapy and in combination with the drug "Doxazosin".

3. If, for any reason, another drug intake has been missed, you can not break the usual schedule of treatment by taking two tablets at once: instead of the expected benefit, you can damage your body.

4. With respect to patients suffering from various types of renal failure, there is no particular need for the selection of therapeutic doses, since during the study of pharmacokinetics it was established that the patient's condition does not affect the excretion of the drug.

5. The same principle applies to elderly people, although finasteride is not as effective from the body of patients older than seventy years old.

Finasteride 5mg for hair loss side effects

The undesirable effects that arise in response to the use of the drug are combined in this list:

  • The immune system can respond to it with symptoms of hypersensitivity.
  • The reaction of the mammary glands and the reproductive system can lead to the development of gynecomastia (a painful enlargement of the mammary glands in men accompanied by hypertrophy of adipose tissue), impotence, pain in the testicles, various ejaculation disorders and a significant decrease in the volume of ejaculated secretion.
  • Patients prone to allergic reactions may experience severe swelling of the face and lips, a rash on the surface of the skin; The patient often complains of hives accompanied by severe itching.
  • The influence of finasteride on the digestive system is manifested by the activation of hepatic enzymes.
  • The circulatory system reacts to finasteride by the development of palpitation (irregular heart muscle functioning).
  • Mental reaction of the body may manifest a significant weakening of sexual desire.
  • In the blood of the patient receiving Finasteride, the concentration of hormones: luteinizing (LH) and follicle stimulating (FSH) can increase, while the content of prostate-specific antigen (PSA) is significantly reduced.

Finasteride Overdose

The administration of a single dose of finasteride in the amount of 400 mg and subsequent regular drug treatment (dosage size - 80 mg during the day) for twelve weeks did not cause any negative symptoms in patients.

The developed recommendations concerning the treatment of patients with an overdose of finasteride are not available at the moment.

Special instructions

- In patients with finasteride, patients who have a significantly reduced outflow of urine or a large volume of residual urine, need careful monitoring of the likely development of obstructive uropathy.

- Before starting treatment, you should make sure there are no diseases that can simulate adenoma of the prostate - stricture of the urethra, prostate cancer, infectious prostatitis, bladder hypotension and all kinds of violations of its innervation.

- Pregnant women and patients of childbearing age should exclude the possibility of contact with finasteride, which has a teratogenic (capable of disrupting the normal course of development of the reproductive organs in male embryos) by action and penetrating into the seminal plasma.

- The reception of finasteride leads to a significant decrease in the level of PSA in the blood. After six months of treatment, it falls by 42%, in a year - by 48%.

To exclude the possibility of developing a malignant tumor of the prostate gland, patients taking finasteride should undergo a regular examination.

Finasteride interactions

Drugs antipyrine, warfarin, propranolol, glyburide, digoxin and theophylline when interacting with finasteride do not lead to the emergence of clinically significant symptoms.

Clinically significant drug interaction is also not observed with the concomitant use of finasteride and non-steroidal anti-inflammatory drugs, quinolones, beta and alpha-adrenoblockers, diuretics, nitrates, ACE inhibitors and HMG-CoA reductase, calcium channel blockers and benzodiazepines.

In patients daily consuming more than 50 ml of alcoholic beverages, the risk of developing prostate cancer is significantly increased, and the positive effect of finasteride on the body is significantly reduced. In a special medical study (covering almost 11,000 men over the age of fifty) over a period of seven years, it was shown that alcohol consumption during the treatment with finasteride increases the risk of developing prostate cancer (both low-grade and low-grade Forms) by almost 90%. Important in this case is the type of alcoholic beverage consumed.

The highest risk is exposed to beer lovers. With the use of natural wine, the probability of developing prostate cancer was the lowest. Scientists emphasize that the negative impact of alcohol is observed only in the case of regular use of sufficiently large doses. If small portions of alcoholic beverages are not used too often, it does not have a particular effect on the risk of developing prostate cancer.

Considering the fact that the metabolism (the change in the drug with the formation of the products of its disintegration - metabolites) of finasteride occurs with the participation of the CYP3A4 isoenzyme, it is undesirable to use it simultaneously with drugs that are inhibitors or inducers of the above isoenzyme, since their effect may affect plasma concentrations of the preparation Blood.

Finasteride for hair loss reviews

Veronica:

My husband suffers from an adenoma of the prostate. The half-year course of treatment with finasteride (the volume of the prostate was sixty-five cubic centimeters) helped to normalize the size of the affected organ and eliminate problems with urination. The use of the drug provoked an unexpected side effect: accelerated growth of hair on the entire surface of the body. Fortunately, for a man it does not really matter. The attending physician said that to take finasteride will have throughout life.

Max:

Being still very young man, I longly drove away from myself the thought that the culprit of the painful symptoms observed by me is prostate adenoma. After a thorough urological examination and confirmation of this diagnosis, I was assigned finasteride. I accept it already for a year. It was possible to achieve a positive result and a significant relief of the condition. An impressive list of side effects listed in the instructions for use, initially aroused fear, but fortunately, none of them (including probable problems with potency) touched me.

Richard:

I was surprised, after reading a review that the reception finasterida led to increased hair growth. I take this drug for just over two years. Before I became acquainted with the effect of this medication, my body was covered with dense vegetation, which could be envied by an anthropoid primacy. Now there is not a hair left on him (even on his feet).

Cheap Finasteride (Propecia) 5mg. How to buy Finasteride?

The cost of Propecia (Finasteride) 5mg mainly depends on the manufacturer, as well as on the place of purchase of the drug. The average price of a package containing thirty tablets (5 mg each) of a drug produced in Canada or India in pharmacies in USA is $40. The same package of finasteride, produced by the Israeli pharmaceutical company Teva, will cost the consumer $50.

For more information about Propecia (Finasteride) prices, click the banner below:

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